DDT full form is DICHLORDIPHYNYLE TRICHLOROETHYLENE ,A highly toxic compund with drastic power. In September 2006, the World Health Organization (WHO) declared its support for the indoor use of DDT in African countries where malaria remains a major health problem, citing that benefits of the pesticide outweigh the health and environmental risks. Since 1996, EPA has been participating in international negotiations to control the use of DDT and other persistent organic pollutants used around the world. DDT was developed in the 1940s as an insecticide, and many countries still use it for malaria control. Custom Label 794241. United States Environmental Protection Agency. Dithiothreitol (DTT) is the common name for a small-molecule redox reagent also known as Cleland's reagent. The United States began to use DDT in large numbers from 1942. Hence, its manufacture was banned in the United States and many other countries in 1994. Following World War II, it was promoted as a wonder-chemical, the simple solution to pest problems large and small. Cases soared from 4,117 in 1995 to 64,622 in 2000. He was awarded Noble prize in medicine and physiology in 1948 for this discovery. DDT was one of the many insecticides in World War II to battle insects carrying diseases such as typhus and malaria. According to the results of total mortality of liver and hepatobiliary cancer, there was a significant downward trend, from 8.8 in 1930 to 8.4 in 1944, to 5.6 in 1972 (both according to 100,000) Artificial base count). DDT's quick success as a pesticide and broad use in the United States and other countries led to the development of resistance by many insect pest species. DDT, DDE, DDD CAS ID #: 50-29-3, 72-55-9, 72-54-8, 72-55-9,72-54-8 Affected Organ Systems: Developmental (effects during periods when organs are developing) , Endocrine (Glands and Hormones), Hepatic (Liver), Neurological (Nervous System), Reproductive (Producing Children) Cancer Classification: EPA: Probable human carcinogen. DDT was applied as an insecticide in agriculture and continues to be used against mosquitoes in several countries to control malaria and leishmaniasis. Contact Us to ask a question, provide feedback, or report a problem. Many species of insects developed resistance to DDT, and DDT was also discovered to have a high toxicity toward fish. The Convention includes a limited exemption for the use of DDT to control mosquitoes that transmit the microbe that causes malaria - a disease that still kills millions of people worldwide. DDT has also been used in the past for the treatment of lice. Moreover, two yeast expression-reporter systems, constructed to test if the DDT isomers and metabolites could transcriptionally activate the hER, demonstrated that an o,p'-DDT metabolite could transactivate the hER or LexA-hER fusion protein with just a 140- to 300-fold weaker potency than that of estradiol . A variety of environmental factors that include toxicants, nutrition and stress have been shown to induce the epigenetic transgenerational inheritance of disease [1, 2] (Figure 1).Examples of such environmental compounds include pesticides [3, 4], fungicide vinclozolin [], hydrocarbons (jet fuel) [], dioxin [], and the plasticizers phthalates and bisphenol A (BPA) []. Uses of DDT. Cases of malaria fell from 400,000 in 1946 to virtually none in 1950 (3). IUPAC name of DDT is 2,2-bis(p-Chlorophenyl)-1,1,1-trichloroethane)DDT. It was initially used with great effect to combat malaria, typhus, and the other insect-borne human diseases among both military and civilian populations. However, certain mutations in insects can make them resistant to DDT. Paul Muller of Geigy Pharmaceuticals in Switzerland was the first person to discover the effectiveness of DDT as an insecticide. O,P'-Ddt | C14H9Cl5 | CID 13089 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Banned pesticide DDT may raise risk of Alzheimer's disease . This is attributed to egg thinning and reduced reproduction rates in some bird species due to egg breakdown and embryo death. It is a colorless crystalline solid and has no taste or smell. DDT is similar in structure to the insecticide methoxychlor and the acaricide dicofol. What is DDT used for? DDT is still used today in South America, Africa, and Asia for this purpose. As a result, today, DDT is classified as a probable human carcinogen by U.S. and international authorities. Get … DDT is popularly known for its insecticidal properties.

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